Pretreatment with metformin protects mice from whole-body irradiation
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چکیده
منابع مشابه
Protective Immunity in Mice with Whole Body of Echinococcus granulosus
Despite the establishment of extensive and successful control programmes in some countries or regions, Echinococcus granulosus still has a very wide geographical distribution. Mature E. granulosus (n = 120) obtained from Parasitology Department, School of Veterinary Medicine, Ferdowsi University of Mashhad (Iran). Soluble protein of whole body of parasite was prepared by freeze-thawing in liqui...
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This experiment was designed to determine the involvement of varying levels of whole-body irradiation on ovarian follicular and corpora luteal development in mice. Previous research has indicated reduced counts of ovarian follicles and corpora lutea in mice flown in space. These differences may be the result of microgravity, increased exposure to radiation, or some combination of both. Fifty-si...
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Background: The study of rheological properties of blood has special interest since it is a circulating fluid exposed to shear rates during its life time. This work aims to investigate the influence of whole body gamma irradiation on the rheological properties of rat’s blood. The applied shear rate was from 12 to 375 s-1. Low shear viscosity (up to 100 s-1) depends mainly on the erythroc...
متن کاملEarly increase in osteoclast number in mice after whole-body irradiation with 2 Gy X rays.
Bone loss is a consequence of exposure to high-dose radiotherapy. While damage to bone vasculature and reduced proliferation of bone-forming osteoblasts has been implicated in this process, the effect of radiation on the number and activity of bone-resorbing osteoclasts has not been characterized. In this study, we exposed mice to a whole-body dose of 2 Gy of X rays to quantify the early effect...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2021
ISSN: 0449-3060,1349-9157
DOI: 10.1093/jrr/rrab012